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How FRONTLINE Plus works.

FRONTLINE Plus is non-systemic.

FRONTLINE Plus has a non-systemic mode of action. FRONTLINE Plus kills parasites through contact, not via the pet's bloodstream.


From where you apply the product, FRONTLINE Plus spreads all over the pet’s body.

It concentrates into the sebaceous glands of the skin and is constantly replenished over the pet’s skin and coat. This ‘store’ gives the product its prolonged efficacy – even after bathing, swimming and grooming.

           Hair follicle coated with
           FRONTLINE Plus


FRONTLINE Plus kills fleas and ticks by affecting their nervous system.

It causes hyperexcitation in these parasites. Disoriented, dying fleas rise to the surface of the pet’s coat – which is why you might actually notice more fleas after applying the product.


FRONTLINE Plus contains two active ingredients to break the flea life cycle at every stage.  One ingredient, fipronil, kills the adult fleas on your pet while the other ingredient, (s)-methoprene, kills fleas eggs and larvae and prevents pupal development.  (s)-methoprene prevents fertile flea eggs being laid, preventing reinfestation of your pet and contamination of your home environment.  Fleas can breed all year round so ensure you continue to treat your pet in winter to achieve the best flea control.






Merial New Zealand Limited, Level 3, Merial Building, Osterley Way, Manukau City, 2241, New Zealand. ®FRONTLINE is a Registered Trademark of Merial Limited.
Registered pursuant to the ACVM Act 1997, Nos. A9008, A9009, A7305 & A10523. See for registration conditions.
©Boehringer Ingelheim 2017. All Rights Reserved.